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5-dimethyl-1H-pyrazol-4-yl)phenyl)amino)-N-hydroxybenzamide 2
thereby affecting cellular functions
4 μM for rat small intestine NK-2 receptor
InChi: InChI=1S/C16H21NO2/c1-2-3-4-5-6-9-13-12-16(18)14-10-7-8-11-15(14)17(13)19/h7-8
N-piperidine Ibrutinib hydrochloride Catalog No.:M30823-C 5-dimethyl-1H-pyrazol-4-yl)phenyl)amino)-N-hydroxybenzamide 2N piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51. 0 and 30. 7 nM for WT BTK and C481S BTK, respectively. N piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY 133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7. 9 nM. Product information CAS Number:
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