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Z-VEID-FMK 5-HT hydrochloride and fourth-step mutants with MIC

SKU: 53385150744

4.8
USD100.00 USD123.00

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Description

and fourth-step mutants with MIC values of 0

Z-VEID-FMK 5-HT hydrochloride and fourth-step mutants with MICWhen compared to other caspase inhibitors, Z DRHD FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor Z Val Ala Asp (OMe) fluoromethy ketone (Z VAD FMK) or the caspase 6 inhibitor Z Val Glu(Ome) Ile Asp(OMe) fluoromethyl ketone (Z VEID FMK). However, it was less effective in inhibiting TNF induced apoptosis than Z VAD FMK or Z VEID FMK, presumably because caspase 6 is only one of at least three effector caspases, the

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