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PNU-120596 causes changes in cysteine accessibility at the inner beta sheet
LY2857785 significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines
CAS Number: 2070015-31-3
CAS Number: 70052-12-9
ATN-161 trifluoroacetate salt Size:Solid 10 mg PNU-120596 causes changes in cysteineATN 161 is a small peptide antagonist of integrin alpha5beta1 with potential antineoplastic activity. ATN 161 selectively binds to and blocks the receptor for integrin alpha5beta1, thereby preventing integrin alpha5beta1 binding. This receptor blockade may result in inhibition of endothelial cell cell interactions, endothelial cell matrix interactions, angiogenesis, and tumor progression. Integrin alpha5beta1 is expressed on endothelial cells and
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