Plecanatide A3-IN-2 24 hours) decreases the viability

24 hours) decreases the viability of A549 and H460 cells with IC50 values of 5

6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model

CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator

Formula: C17H30O10

Plecanatide A3-IN-2 24 hours) decreases the viabilityPlecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase C (GC C) receptor agonist. Plecanatide activates GC C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti inflammatory activity in models of murine colitis. Product information CAS Number: 467426 54 6 Molecular Weight: 1681. 89 Formula: C65H104N18O26S4 Chemical Name: (4S) 4 [(2S) 2 [(2S) 2 amino 3 carbamoylpropanamido] 3