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Molecular Weight: 357
InChi: InChI=1S/C34H52N2O4/c37-33(35(27-15-5-1-6-16-27)28-17-7-2-8-18-28)25-39-31-23-13-14-24-32(31)40-26-34(38)36(29-19-9-3-10-20-29)30-21-11-4-12-22-30/h13-14
1 μM for both GNE-7915 (100-fold over LRRK2 Ki) and 19 (250-fold over LRRK2 Ki) resultes in only TTK showing greater than 50% inhibition
DB07268 (Compound 2b) also inhibits CHK1
CZC-25146 - CAS# 1191911-26-8 0088 Molecular Weight: 357CZC 25146, CAS No. 1191911 26 8, is a potent and selective LRRK2 inhibitor. Leucine rich repeat kinase 2 (LRRK2) mutations are the most important cause of familial Parkinson's disease. CZC 25146 prevents mutant LRRK2 induced injury of cultured rodent and human neurons with mid nanomolar potency. Product information CAS Number: 1191911 26 8 Molecular Weight: 488. 54 Formula: C22H25FN6O4S Synonym: CZC25146 CZC 25146 CZC 25146 Chemical Name: N (2 ((5
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