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) increases pHH3 in a dose-dependent manner and significantly inhibits the growth of HT-29 colorectal cancer xenografts
Epub 2013 Feb 4
PubMed Central PMCID: PMC5015966
It is completely inactive against type II and type III PRMTs
YM-201636 - CAS# 371942-69-7 size:2mg solid ) increases pHH3 in aYM 201636, CAS No. 371942 69 7, is an inhibitor of retroviral budding and PIKfyve catalyzed PtdIns(3, 5)P2 synthesis, and can also halt glucose entry by insulin in adipocytes. YM 201636 almost completely inhibited basal and insulin activated 2 deoxyglucose uptake at doses as low as 160 nM, with IC(50)=54+ 4 nM for the net insulin response. Insulin induced GLUT4 translocation was partially inhibited at substantially higher doses, comparable to those
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