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EL-102 islignan 18H-oxacyclotetradeca[3

SKU: 44032863077

4.3
USD100.00 USD142.00

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Description

18H-oxacyclotetradeca[3

Smiles: NC(N)=NCCC[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSCCC(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@@H](CC2C=CC=CC=2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O

6-tetrahydropyrimidine

Chemical Name: disodium (2S)-3-(1H-indol-3-yl)-2-[(2S)-4-methyl-2-{[oxido({[(2S

EL-102 islignan 18H-oxacyclotetradeca[3EL102 is a inhibitor of HIF1 , Which can inhibit tubulin polymerisation and decreased microtubule stability. target: HIF1IC 5020 40 nM. in vitro : EL102 is a cytotoxic agent and also displays cytostatic properties, through flow cytometric analysis of PI stained cells cultured for 24, 48 and 72 h, following treatment. EL102 induces apoptosis and causes G2 M arrest, preventing the cell from entering into mitosis. In vivo: CWR22 tumours were taken from

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