Pay in 4 interest-free payments of $30.00 Learn more
Ships within 48 hours · Estimated delivery Jul 26 - Jul 31
PubMed PMID: 28742863
InChi: InChI=1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14)15-10-23-26(12-15)7-8-27/h2-6
InChi: InChI=1S/C17H13Br2N5OS/c1-9-15(24-5-3-4-20-16(24)21-9)13-8-26-17(22-13)23-14-11(18)6-10(25-2)7-12(14)19/h3-8H
Optimizing management of ruxolitinib in patients with myelofibrosis: the need for individualized dosing
GW791343 dihydrochloride 022 PubMed PMID: 28742863GW791343 dihydrochloride is a P2X7 allosteric modulator; exhibits species specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6. 9 7. 2). IC50 value: 7 (pIC50) Target: P2X7 in vitro: In cells expressing human P2X7 receptors, GW 791343 inhibits agonist stimulated ethidium accumulation in both sucrose and NaCl buffer. In NaCl buffer, GW 791343 reduces the maximal response to both ATP and BzATP, but there is little effect
US$ 65.00
US$ 125.00
US$ 38.00
US$ 65.00
US$ 38.00
US$ 38.00
US$ 80.00
US$ 38.00
US$ 38.00