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Epub 2014 May 27
12-dihydroxy-15-{[(2R
InChiKey: QWUHPPCZZXKXOQ-UHFFFAOYSA-N
Actinomycin D was the first antibiotic shown to have anti-cancer activity
UPF-648 0532223 Epub 2014 May 27UPF 648 is a kynurenine 3 monooxygenase (KMO) inhibitor. UPF 648 binds close to the FAD cofactor and perturbs the local active site structure, preventing productive binding of the substrate l kynurenine. UPF 648 may be potentially useful for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's diseases. Product information CAS Number: 213400 34 1 Molecular Weight: 259. 09 Formula: C11H8Cl2O3 Chemical Name: (1S,2S) 2 (3,4
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