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an anti-CTLA 4 monoclonal antibody
InChi: InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10
Formula: C13H13N3OS
Letourneau R
AZD5363 agillin an anti-CTLA 4 monoclonal antibodyAZD5363, also known as Capivasertib, is an orally available inhibitor of the serine threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AKT inhibitor AZD5363 binds to and inhibits all AKT isoforms. Inhibition of AKT prevents the phosphorylation of AKT substrates that mediate cellular processes, such as cell division, apoptosis, and glucose and fatty acid metabolism. A wide range of solid and hematological